This post was published more than a few years ago (on 2007-02-07) and may contain inaccurate technical information, outmoded thoughts, or cringe takes. Proceed at your own risk.
HowTube Episode 5 [No longer online —Ed. 2015-08-14] shows you how to use the beta DarwiinRemote software to control your Mac with your Wiimote. Yes, it’s a bit silly, but it’s fun!